Sixth Season Opener - After an explosion destroys Community General Hospital, Steve Sloan helps FBI agent Wagner search the rubble for his missing father and the rest of the team. After the dust settles, the hunt for Caitlin Sweeney begins. It's discovered that the Sweeney's belong to a terrorist organization, R.O.A.R.
Two fiancées plot to murder the bride's father on their wedding day. The two review their perfect plan the night before the wedding. Unfortunately murder is never as easy as one might plan.
When Steve assigns two police officers from the vice squad to assist in solving the homicide of a local pimp, things do not go according to plan.
They uncover four corrupt female homicide cops who murder felons to harvest their organs for those more deserving.
Dr. Sloan investigates when a good friend is wrongfully accused of murder. Amanda and Jack help Mark investigate the deceased's employees, all three of whom had a legitimate motive.
The hospital is the scene of a manhunt when a corpse comes to life and attacks Amanda, then leads Steve and the police on a chase throughout the entire building during which he kidnaps Jesse's girlfriend Susan. Mark learns the fugitive is on the run from NSA agents, who claim he's an international terrorist.
Jesse's car breaks down while he and Susan are on their way to a fun-filled vacation in Carmel. The two are stranded in a small town where Susan spies a supposedly long dead beau, Greg. They eventually discover that he faked his death in order to plunder a shipwrecked vessel undetected. The townsfolk, all in on the scheme, murder Greg and pin the blame on Jesse and Susan.
When a best-selling mystery author comes down with writer's block, she commits a murder herself in the hopes of stimulating her creative juices. The delusional author has help from her fictional heroine, Danielle Slade.
Mark stumbles onto a kidnapping case when the kidnapper accidentally calls the Sloan residence with a ransom demand. Steve runs to phone booths across the city a la Dirty Harry to safely rescue the child.
Amanda enlists Jesse's computer-nerd friends to find a killer, after she accidentally surfs across an on-line murder. Meanwhile, Jesse's girlfriend, Susan, comes down with a case of food poisoning after dining at Barbecue Bob's.
Mark stumbles onto a kidnapping case when the kidnapper accidentally calls the Sloan residence with a ransom demand. Steve runs to phone booths across the city a la Dirty Harry to safely rescue the child.
Shadowy figures haunt Jesse after he returns after being missing five days and believes aliens may have abducted him. Mark and Steve try to figure out what happened to him, while Jesse tries to stave off hallucinations, clandestine midnight meetings, and secretive government agents.
Jesse's car breaks down while he and Susan are on their way to a fun-filled vacation in Carmel. The two are stranded in a small town where Susan spies a supposedly long dead beau, Greg. They eventually discover that he faked his death in order to plunder a shipwrecked vessel undetected. The townsfolk, all in on the scheme, murder Greg and pin the blame on Jesse and Susan.
Two fiancées plot to murder the bride's father on their wedding day. The two review their perfect plan the night before the wedding. Unfortunately murder is never as easy as one might plan.
Newly retired detective Harry Trumble returns to the force when it appears 'The Clown Killer', a murderer Trumble chased for more than a decade, has emerged from obscurity to kill again. Mark is reluctant to help Harry investigate the Clown, in part due to a rift between the two, but also because Mark suspects Harry has something to do with the Clown's reappearance.